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SymptomsThe symptoms of this condition consist of:An upper respiratory tract infection could precede all other symptoms in as a lot of as 68.8% of patientsA single, 2- to 10-cm oval red "herald" patch appears, classically on the abdomen. Occasionally, the "herald" patch may possibly happen in a 'hidden' position (in the armpit, for example) and not be noticed immediately. The "herald" patch may also appear as a cluster of smaller oval spots, and be mistaken for acne. Rarely, it does not turn into present at all.7-14 days after the herald patch, big patches of pink or red, flaky, oval-shaped rash appear on the torso. In 6% of cases an inverse distribution may happen, with rash mostly on the extremities. The more several oval patches typically spread widely across the chest initial, following the rib-line in a characteristic "christmas-tree" distribution. Small, circular patches may appear on the back and neck several days later. It is unusual for lesions to form on the face, but they could appear on the cheeks or at the hairline.About one-in-four individuals with PR suffer from mild to severe symptomatic itching. (Moderate itching due to skin over-dryness is significantly much more common, especially if soap is utilized to cleanse the affected areas.) The itching is frequently non-certain, and worsens if scratched. This tends to fade as the rash develops and does not generally last by way of the entire course of the illness.The rash may be accompanied by low-grade headache, fever, nausea and fatigue. Over-the-counter medications can aid manage these. DiagnosisHerald lesion of PR (second lesion above the ankle, approximately in the center of the plate) depicted 21 days following initial encounter. The patient had an episode of sore throat, that was treated with a strong antibiotic without success. The lesion appeared approximately one week following the end of the upper respiratory tract infection.Experienced doctors may possibly make the diagnosis clinically. If the diagnosis is in doubt, tests may possibly be performed to rule out comparable conditions such as ringworm, guttate psoriasis, nummular or discoid eczema, drug eruptions, other viral exanthems, and specifically secondary syphilis. A biopsy of the lesions will show extravasated erythrocytes inside dermal papillae and dyskeratotic cells within the dermis. TreatmentNo treatment is usually necessary.Oral antihistamines or topical steroids might be used to decrease itching. Steroids do provide relief from itching, and increase the appearance of the rash, but they also trigger the new skin that forms (right after the rash subsides) to take longer to match the surrounding skin color. Even though no scarring has been found to be associated with the rash, itching and scratching ought to be avoided. Irritants such as soap really should be avoided, too a soap containing moisturizers (such as goat's milk) may possibly be employed, even so, any generic moisturizer can support to manage over-dryness.[citation needed]Direct sunlight makes the lesions resolve much more quickly. According to this principle, medical treatment with ultraviolet light has been utilized to hasten resolution, although studies disagree whether or not it decreases itching or not. UV therapy is most beneficial in the initial week of the eruption. PrognosisIn most patients, the condition lasts only a matter of weeks in some circumstances it can last longer (up to six months). The illness resolves totally without having lengthy-term effects. Two percent of patients have recurrence. EpidemiologyThe overall prevalence of PR in the United States has been estimated to be .13% in men and .14% in females. It most commonly occurs between the ages of 10 and 35. It is far more common in winter. See alsoPityriasis circinata - a localized form of pityriasis rosea that affects the axillae and groinPityriasis - for list of similarly named flaky skin conditions References^ Freedberg et al (2003), Fitzpatrick's Dermatology in General Medicine (6th ed.), McGraw-Hill, p. 445, ISBN 0071380760 ^ James, William Berger, Timothy Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. pp. 208-9. ISBN 0721629210. ^ a b c d e f g h i j Habif, Thomas P (2004), Clinical Dermatology: A Clinical Guide to Diagnosis and Therapy (4th ed.), Mosby, pp. 246-8, ISBN -323-01319-8 ^ "Pityriasis rosea". DERMAdoctor.com. http://www.dermadoctor.com/article_Pityriasis-Rosea_60.html. Retrieved 26 Jan 2010. ^ "Pityriasis rosea". American Osteopathic College of Dermatology. http://www.aocd.org/skin/dermatologic_diseases/pityriasis_rosea.html. Retrieved 26 Jan 2010. ^ Sharma, P (2000). J Am Acad Dermatol 42 (2 pt 1): 241. ^ a b c d e f "Pityriasis rosea". American Academy of Dermatology. 2000, 2003. http://www.aad.org/public/publications/pamphlets/typical_pityriasis.html. Retrieved 2009-06-04. ^ Tay, Y Goh, C (829). "1-year review of pityriasis rosea at the National Skin Centre, Singapore". Ann Acad Med Singapore 28 (6). ^ Horn T, Kazakis A (1987). "Pityriasis rosea and the require for a serologic test for syphilis". Cutis 39: 81. ^ a b c Arndt, KA (1983). "Treatment of pityriasis rosea with UV radiation". Arch Dermatol 119: 381. ^ Leenutaphong V, Jiamton S (1995). "UVB phototherapy for pityriasis rosea: a bilateral compatison study". J Am Acad Dermatol 33 (6): 996. ^ Kempf, W et al (1999). "Pityriasis rosea is not connected with Human herpesvirus 7". Arch Dermatol 135 (9): 1070. ^ Chuang, T-Y et al (1982). "Pityriasis rosea in Rochester, Minnesota, 1969 to 1978: a 10-year epidemiologic study". J Am Acad Dermatol 7: 80. External linksAmerican Academy of Dermatology - Pityriasis RoseaeMedicine.com - Pityriasis RoseaWebMD.com - Pityriasis RoseaHealthInPlainEnglish - Pityriasis roseaDermNet viral/pityriasis-roseahttp://www.aocd.org/skin/dermatologic_diseases/pityriasis_rosea.html Pityriasis Rosea overviewLinks to pityriasis rosea pictures (Hardin MD/Univ of Iowa)Go Ask Alice Health Assistance from Columbia UniversityAmerican Osteopathic College of Dermatologyv  d  eDiseases of the skin and appendages by morphologyGrowthsEpidermalwart callus seborrheic keratosis acrochordon molluscum contagiosum actinic keratosis squamous cell carcinoma basal cell carcinoma merkel cell carcinoma nevus sebaceous trichoepitheliomaPigmentedFreckles lentigo melasma nevus melanomaDermal andsubcutaneousepidermal inclusion cyst hemangioma dermatofibroma keloid lipoma neurofibroma xanthoma Kaposi's sarcoma infantile digital fibromatosis granular cell tumor leiomyoma lymphangioma circumscriptum myxoid cystRashesWithepidermalinvolvementEczematouscontact dermatitis atopic dermatitis seborrheic dermatitis stasis dermatitis lichen simplex chronicus Darier's disease glucagonoma syndrome langerhans cell histiocytosis lichen sclerosus pemphigus foliaceus Wiskott-Aldrich syndrome Zinc deficiencyScalingpsoriasis tinea (corporis cruris pedis manuum faciei) pityriasis rosea secondary syphillis mycosis fungoides systemic lupus erythematosus pityriasis rubra pilaris parapsoriasis ichthyosisBlisteringherpes simplex herpes zoster varicella bullous impetigo acute contact dermatitis pemphigus vulgaris bullous pemphigoid dermatitis herpetiformis porphyria cutanea tarda epidermolysis bullosa simplexPapularscabies insect bite reactions lichen planus miliaria keratosis pilaris lichen spinulosus transient acantholytic dermatosis lichen nitidus pityriasis lichenoides et varioliformis acutaPustularacne vulgaris acne rosacea folliculitis impetigo candidiasis gonococcemia dermatophyte coccidioidomycosis subcorneal pustular dermatosisHypopigmentedtinea versicolor vitiligo pityriasis alba postinflammatory hyperpigmentation tuberous sclerosis idiopathic guttate hypomelanosis leprosy hypopigmented mycosis fungoidesWithoutepidermalinvolvementRedBlanchableErythemaGeneralizeddrug eruptions viral exanthems toxic erythema systemic lupus erythematosusLocalizedcellulitis abscess boil erythema nodosum carcinoid syndrome fixed drug eruptionSpecializedurticaria erythema (multiforme migrans gyratum repens annulare centrifugum ab igne)NonblanchablePurpuraMacularthrombocytopenic purpura actinic purpuraPapulardisseminated intravascular coagulation vasculitisInduratedscleroderma/morphea granuloma annulare lichen sclerosis et atrophicus necrobiosis lipoidicaMiscellaneousdisordersUlcersHairtelogen effluvium androgenic alopecia trichotillomania alopecia areata systemic lupus erythematosus tinea capitis loose anagen syndrome lichen planopilaris folliculitis decalvans acne keloidalis nuchaeNailonychomycosis psoriasis paronychia ingrown nailMucousmembraneaphthous stomatitis oral candidiasis lichen planus leukoplakia pemphigus vulgaris mucous membrane pemphigoid cicatricial pemphigoid herpesvirus coxsackievirus syphilis systemic histoplasmosis squamous cell carcinomav  d  eDiseases of the skin and subcutaneous tissue (integumentary system) (L, 680-709)InfectionsBacterialskin diseaseStaphylococcus (Staphylococcal scalded skin syndrome, Impetigo, Boil, Carbuncle) Strep (Impetigo) Corynebacterium (Erythrasma)Viralskin diseaseWart Molluscum contagiosum Erythema infectiosum Exanthema subitum Herpes simplex (Herpetic whitlow, Eczema herpeticum)GeneralCellulitis (Paronychia) Acute lymphadenitis Pilonidal cyst Pimple (Pustule)Bullousdisordersacantholysis (Pemphigus, Transient acantholytic dermatosis) Pemphigoid (Bullous, Cicatricial, Gestational) Dermatitis herpetiformisInflammatoryDermatitisand eczemaAtopic dermatitis Seborrhoeic dermatitis (Dandruff, Cradle cap) Contact dermatitis (Diaper rash, Urushiol-induced contact dermatitis) Erythroderma Lichen simplex chronicus/Prurigo nodularis Itch (Pruritus ani, Pruritus scroti, Pruritus vulvae) Nummular dermatitis Dyshidrosis Pityriasis albaPapulosquamousdisordersPsoriasis (Psoriatic arthritis) Parapsoriasis (Pityriasis lichenoides et varioliformis acuta, Pityriasis lichenoides chronica, Lymphomatoid papulosis) other pityriasis (Pityriasis rosea, Pityriasis rubra pilaris) other lichenoid (Lichen planus, Lichen nitidus)UrticariaDermatographic urticaria Cold urticaria Cholinergic urticaria Solar urticariaErythemaErythema multiforme/drug eruptionStevens-Johnson syndrome Toxic epidermal necrolysis Erythema nodosum  Acute generalized exanthematous pustulosisOther erythemaErythema annulare centrifugum Erythema marginatum Keratolytic winter erythema Necrolytic migratory erythema Erythema toxicumRadiation-relateddisordersSunburn actinic rays (Actinic keratosis, Actinic cheilitis) Polymorphous light eruption (Acne aestivalis) Radiodermatitis Erythema ab ignePigmentation/Dyschromiahypopigmentation (Albinism, Vitiligo) hyperpigmentation (Melasma, Freckle, Caf au lait spot, Lentigo/Liver spot, Acanthosis nigricans, Acral acanthotic anomaly)Other skinkeratosis/hyperkeratosis (Seborrheic keratosis, Callus) other epidermal thickening (Ichthyosis acquisita, Palmoplantar keratoderma)skin ulcer (Pyoderma gangrenosum, Bedsore)Cutaneous Markers of Internal Malignancy (Florid cutaneous papillomatosis, acanthosis nigricans, sign of Leser-Trelat)atrophic (Lichen sclerosus, Acrodermatitis chronica atrophicans)necrobiosis (Granuloma annulare, Necrobiosis lipoidica) other granuloma (Granuloma faciale, Pyogenic granuloma)cutaneous vasculitis (Livedoid vasculitis, Erythema elevatum diutinum)Connectivetissuescollagen illness: Keloidlocalized connective tissue disorders: Lupus erythematosus (Discoid lupus erythematosus, Subacute cutaneous lupus erythematosus) Scleroderma/Morphea Linear scleroderma Calcinosis cutis Sclerodactyly Ainhumintegument, SF, LCT navs: anat/physio, noncongen/congen/neoplasia, symptoms+signs/eponymous, proc Categories: Papulosquamous hyperkeratotic skin diseases | Ailments of unknown etiologyHidden categories: All articles with unsourced statements | Articles with unsourced statements from January 2009
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